I use the Palomar Knot for most of my fishing applications. I have found it to be a strong knot, and dependable with fluorocarbon. Wetting the knot before cinching it is an important step for tying the Palomar, because it helps reduce line friction. Another important step in tying the Palomar is making sure you apply equal pressure on both the main line, and the tag end when cinching down the knot.
If you are that worried about the knot failing, you can also tie a Double Palomar knot. It is tied very much the same way . The one difference between the Palomar, and the Double Palomar is, instead tying one over hand knot, the Double Palomar Knot is tied with two over hand knots before the lure, or hook is passed through the loop and cinched down. I normally tie the Double Palomar knot when I use braid. The second over hand knot is extra insurance to protect against line slippage.